5F-APINACA (5F-AKB48) (also known as 5F-AKB48 or 5-fluoro APINACA or APINACA 5-fluoropentyl analog) is an indazole-based synthetic cannabinoid that has been sold online as a designer drug.

5F-AKB48 is a synthetic cannabinoid and chemical analogue of the parent compound AKB48. It has very close chemical resemblance to AKB48 however with a fluoro atom attached, giving the compound a distinctive set of properties.

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AB-PINACA is the latest synthetic drug that can serve as a legal and highly effective alternative to cannabis. While the production, and sale of cannabis may be illegal in most countries, AB-PINACA faces no such issues. It is completely legal to buy and use AB-PINACA, and you will be certain to find the effects of this drug very enjoyable. AB-PINACA is highly potent and even a few milligrams of the powder are enough to give you a substantial hit. The onset of this designer drug is quick and you can experience the effects of AB-PINACA within minutes of imbibing it.
it contains nine deuterium atoms at the 2, 2’, 3, 3’, 4, 4’, 5, 5, and 5 positions. It is intended for use as an internal standard for the quantification of it by GC- or LC-mass spectrometry (MS). AB-PINACA is a synthetic cannabinoid which has recently been identified in illegal herbal products.1 Structurally, this designer drug is developed on an indazole base, which distinguishes it from the many JWH compounds having an indolyl base.1,2 it should not be confused with it(also called AKB48; Item No. 11566), another indazole designed with a carboxamide moiety.3 The biochemical, physiological, and toxicological properties of it have not been determined. This product is intended for research and forensic applications
it is a compound that was first identified as a component of synthetic cannabis products in Japan in 2012. It was originally developed by Pfizer in 2009 as an analgesic medication

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5F-AKB48 is a more potent form of AKB-48, which acts upon the cannabinoid receptors, and is a key component of many synthetic cannabis blends. 5F-AKB48, or N-(adamantan-1-yl)-1-(5-fluoropentyl)-1H-indazole-3-carboxamide, is a synthetic indazole cannabinoid as it contains a substituted indazole group.

Although this substance has not been formally studied, from analysis of the structure, it is presumed that 5F-AKB48 has a similar binding profile to that of other cannabinoids and matches many of the in vivo properties of Δ9-THC. However, the role of these interactions and how they result in the cannabinoid high continues to remain elusive.